+4 9 (0) 60 7 4 487 6 0
standing the test of time

Parainfluenza Virus

Parainfluenza viruses are a group of four distinct serotypes of single-stranded RNA viruses belonging to the paramyxovirus family. They are the second most common cause of flulike respiratory tract infection in younger children.

The viruses are transmitted by droplet infection. Mainly affected are small children till the age of 3 years in temperate climate zones. A seasonal accumulation of infections in cool seasons can be recognized. Generalized contamination levels in the population are already high in childhood, 90% in 10-year-old children.

Parainfluenza viruses primary attach the pharyngeal mucosa, but can spread on the whole tracheobronchial tract. Heavy inflammatory reactions with the distribution of proinflammatoric zytocines occur, may accompanied by an epiglottis. The excessive mucous secretion may leads to the obstructions of the respiratory tract - especially in younger children.

Parainfluenza viruses type 1 and 3 cause a flulike infection in small children accompanied by fever, cough, rhinitis, bronchitis and pseudo croup. Pneumonias can occur. Bacterial superinfections are frequent, as are the usually harmless reinfections.

Infections by Parainfluenza viruses type 2 lead to similar clinical symptoms like with the type 1 and 3, the course of infection is milder.

Species

Disease

Symptoms

Mechanism of Infection

Parainfluenzavirus
(1, 2 und 3)

The majority of infections cause an unspecific disease of the upper and lower respiratory tract in younger children. Infections in adults are rare with a milder course of infection

Mild influenzalike diseases; fever, headache, cough, pharyngitis, bronchitis

Complications:
broncheapneumonia, pseudo croup, bacterial superinfection

Direct or indirect contact with contaminated material,
mainly droplet- and smear infection

Infections may be diagnosed by:

  • Immunofluorescent microscopy
  • Serology:    Determination of specific antibodies by ELISA

NovaLisaTM Parainfluenza virus IgA/IgG ELISA:

The NovaLisaTM Parainfluenza virus IgA/IgG ELISA is intended for the qualitative determination of IgA-/IgG- class antibodies against Parainfluenza viruses in human serum or plasma (citrate).

Antigens:

Purified Parainfluenza virus antigens

Specific performance characteristics:

Intraassay

Interassay

Sensitivity

Specificity

n

Mean

CV%

n

Mean

CV%

IgA

8

1.12

2.6

24

1.07

5.1

>90%

>90%

IgG

8

0.15

6.8

3

21.9

9.8

>95%

>95%

8

1.03

1.6

Order information:

ELISA

Number of Determinations

Product Number

Parainfluenza IgA

96

PAIA0360

Parainfluenza IgG

96

PAIG0360

 

 

Your Partner

Customer Service

info(at)novatec-id.com

Download

Product Insert

Parainfluenza IgA