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Lyme Borrelia Canine
Lyme disease (Borreliosis) is a tick-borne, bacterial disease of domestic animals and humans. It is caused by spirochetes of the Borrelia burgdorferi sensu lato group.
Borrelia are helically wound, flexible, highly motile bacteria. By rotation of their axial filaments (periplasmatic flagella) they are able to move efficiently in corkscrew fashion through viscous media (serum). Thereby they can disseminate throughout the body within days to weeks of infection.
In Europe, the most frequently isolated pathogenic genospecies of humans and dogs are Borrelia afzelii, Borrelia garinii and Borrelia burgdorferi sensu stricto.
The pathogens are transmitted by various tick species of the genus Ixodes. In Europe, Ixodes ricinus is the most important vector. However, infestation rates with Borrelia vary depending on the region. In endemic areas of Germany, approximately 3-7% of the larvae and 10-34% of nymphs and adult ticks are infected by Borrelia burgdorferi sensu lato. Natural reservoirs are wild animals, including rodents as well as many other small mammals and birds. The ticks take their blood meals from these hosts.Since dogs frequent the areas ticks live, they are more affected than humans. Typical tick habitats are the edge of the woods, bushes, undergrowth and tall grass; but infected ticks can also be found in public parks.
Symptoms of Lyme disease in dog comprise fever, apathy, loss of appetite and anorexia as well as recurrent and shifting lameness and polyarthritis. The characteristic rash or the circular area of redness around the bite (erythema chronicum migrans) which is seen in man may be absent or is overlooked due to hair coat or dark pigmentati
Species | Disease | Symptoms | Mechanism of Infection |
Borrelia burgdorferi sensu lato | Lyme disease (Borreliosis) | Fever Apathy Loss of Appetite and anorexia Recurrent and shifting lameness, polyarthritis | Transmission by the bite of an infected tick In Europe by Ixodes ricinus |
Infections may be diagnosed by:
- Microscopy: direct detection and identification of the pathogen is possible but uncertain
- Culture: time-consuming and labor-intensive
- PCR
- Serology: determination of specific antibodies based on the ELISA-technique (screening) or Western-Blot (confirmatory test)
Lyme Borrelia Canine IgG - ELISA:
The NovaTec Lyme Borrelia Canine IgG - ELISA is intended for the qualitative determination of IgG-specific antibodies against Borrelia burgdorferi in canine serum.
Antigens:
VlsE (recombinant) and purified antigens from B. burgdorferi, B. afzelii, B. garinii
Specific performance:
Intraassay | Interasay | Sensitivity | Specificity | |||||
n | Mean | CV% | n | Mean | CV% | |||
IgG | 24 | 1.95 | 2.0 | 12 | 59.2 | 3.6 | 93.3 | >95 |
Order information:
ELISA | Number of Determinations | Product Number |
Lyme Borrelia Canine IgG | 96 | BORG0320V |
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